Pau d’arco is prepared from the inner bark of a flowering South American tree and contains distinctive naphthoquinones, particularly lapachol and beta-lapachone, along with flavonoids and other phenolic compounds. Laboratory research suggests antioxidant, inflammation-modulating, and antimicrobial activity, but direct human cosmetic evidence is limited. It is best presented as a traditional clarifying and soothing botanical rather than a proven treatment for skin disease.
Antioxidant & Environmental Support
• Contains flavonoids, phenolic compounds, and quinones that demonstrate antioxidant activity in laboratory research.
• May help protect the skin’s surface from oxidative stress associated with environmental exposure.
• Can support formulas intended for dull, stressed, or mature-looking skin, although clinical anti-aging benefits have not been established.
Calming & Skin-Comfort Support
• Bark extracts have reduced inflammatory signaling in laboratory and ex vivo research.
• May contribute soothing botanical support to products intended for temporarily uncomfortable or stressed-looking skin.
• Evidence is not sufficient to claim that pau d’arco treats eczema, psoriasis, dermatitis, arthritis, or inflammatory disease.
Clarifying & Microbial-Balance Potential
• Lapachol, beta-lapachone, and bark extracts have demonstrated activity against certain bacteria and fungi under laboratory conditions.
• May support targeted cleansing or clarifying formulas intended for oily, congested, or environmentally challenged skin.
• Laboratory antimicrobial activity does not establish that the bark treats acne, fungal infections, wounds, or other medical conditions.
Traditional Topical Use
• Traditionally prepared as decoctions, washes, baths, and compresses in parts of Central and South America.
• Historical applications included cleansing minor skin concerns and supporting areas affected by discomfort or irritation.